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Solgar Inositol 500 mg Vegetable Capsules - Vitamin B8 - Vegan, Vegetarian, Kosher, 50 Count (Pack of 1)

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One six-month study in 80 postmenopausal women with metabolic syndrome found that 4 grams per day of inositol improved insulin sensitivity, blood pressure and cholesterol levels more than a placebo ( 10). Fertility - Raffone E, Rizzo P, Benedetto V Insulin sensitiser agents alone and in co-treatment with r-FSH for ovulation induction in PCOS women Gynecol Endocrinol. (2010 Apr)

Moroni RF, Cazzaniga E, Palestini P, Sculati M. The feasibility of a diet which enhances inositol availability. Prog Nutr. 2021;23(2). doi:10.23751/pn.v23i2.10356 Bizzarri M, Fuso A, Dinicola S, Cucina A, Bevilacqua A Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease. Expert Opin Drug Metab Toxicol. (2016-Oct) Chatree S, Thongmaen N, Tantivejkul K, Sitticharoon C, Vucenik I Role of Inositols and Inositol Phosphates in Energy Metabolism. Molecules. (2020-Nov-01) D. and R. Tal, Inositol Treatment and ART Outcomes in Women with PCOS. Int J Endocrinol, 2016. 2016: p. 1979654. Dekker, H.T., et al., Maternal folic acid use during pregnancy, methylenetetrahydrofolate reductase gene polymorphism, andchild’s lung function and asthma. Clinical and Experimental Allergy, 2018. 48(2): p. 175-185.When applied to the skin: There isn't enough reliable information to know if inositol is safe or what the side effects might be. Pregnancy: Inositol is possibly safe when taken by mouth, short-term. Doses of up to 4000 mg of myo-inositol daily have been used with apparent safety. Concerto C, Chiarenza C, Di Francesco A, Natale A, Privitera I, Rodolico A, Trovato A, Aguglia A, Fisicaro F, Pennisi M, Bella R, Petralia A, Signorelli MS, Lanza G Neurobiology and Applications of Inositol in Psychiatry: A Narrative Review. Curr Issues Mol Biol. (2023-Feb-20)

It’s important to be wary of products that include sweeteners, vitamins, and other ingredients. The addition of these other ingredients amounts to a “marketing maneuver” and may inhibit gut absorption [ 53]. Studies have found that inositol may be beneficial for improving the function of the ovaries and fertility in women with PCOS ( 16, 17, 18).

With 750mg inositol in each of these capsules, it’s easier than ever to supplement your daily inositol intake. Women with PCOS are at a higher risk of several diseases and can experience infertility issues ( 15). A 2017 randomised controlled crossover study was carried out to investigate which is more effective between metformin and myo inositol on hormonal, clinical and metabolic parameters in obese patients with PCOS. In the study, 34 PCOS obese women were randomised to receive metformin (850mg twice daily) or myo-inositol (1000mg twice daily) for 6 months. After a 3-month washout period, the same subjects received the other compound for the following 6 months. Results showed that both treatments improved the glyco-insulinaemic features of obese PCOS patients, but only metformin seems to exert a beneficial effect on the endocrine and clinical features of the syndrome. 27 Kofman O, Einat H, Cohen H, Tenne H, Shoshana C The anxiolytic effect of chronic inositol depends on the baseline level of anxiety. J Neural Transm (Vienna). (2000)

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